The Northeast of Creation is a Bad Place™. There are powerful Raksha there, and Wyld Maelstroms swirl constantly. In the very eye of the chaos, all is calm, as Crushing Soul of Bronze eternally screams his timeless wrath.
Generally, going there is deadly. Going there with Integrity Protecting Prana is slightly less deadly, but only moves from instant death to fighting incomprehensible beings of primordial chaos (start with “Omnia Vincet Amour,” an infinitely expansive vacuum which contains all things. Then Oroboros the Self-Defeating. Basically, this should be a very bad time, based purely on the power of narrative).